Gene information
Official symbol IL34
Official full name interleukin 34
Gene type protein-coding gene
Chromosome16q22.1
Alias symbolMGC34647; IL-34
Previous symbolC16orf77
Gene familyInterleukins
Resources
Entrez Gene 146433
HGNC HGNC:28529
Ensembl ENSG00000157368
Vega OTTHUMG00000137581
UCSC uc002ezh.2
GO terms: 37 records
GO Description Category LogP Number of genes Detail
GO:0005125 cytokine activity GO Molecular Functions -54.7097150 57 More
GO:0005126 cytokine receptor binding GO Molecular Functions -41.4908940 50 More
GO:0006954 inflammatory response GO Biological Processes -86.5569367 100 More
GO:0010720 positive regulation of cell development GO Biological Processes -17.713649 52 More
GO:0014013 regulation of gliogenesis GO Biological Processes -13.3514185 26 More
GO:0014015 positive regulation of gliogenesis GO Biological Processes -11.0528361 19 More
GO:0030335 positive regulation of cell migration GO Biological Processes -66.7331035 139 More
GO:0030545 signaling receptor regulator activity GO Molecular Functions -87.4728446 102 More
GO:0030546 signaling receptor activator activity GO Molecular Functions -90.4065983 101 More
GO:0032103 positive regulation of response to external stimulus GO Biological Processes -58.7273809 118 More
GO:0033674 positive regulation of kinase activity GO Biological Processes -29.8538991 87 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0042063 gliogenesis GO Biological Processes -20.3412228 47 More
GO:0043405 regulation of MAP kinase activity GO Biological Processes -18.9267681 42 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043410 positive regulation of MAPK cascade GO Biological Processes -49.4744054 112 More
GO:0043549 regulation of kinase activity GO Biological Processes -36.8507249 123 More
GO:0045655 regulation of monocyte differentiation GO Biological Processes -2.92503639 5 More
GO:0045685 regulation of glial cell differentiation GO Biological Processes -7.97684638 17 More
GO:0045687 positive regulation of glial cell differentiation GO Biological Processes -7.00526019 12 More
GO:0045859 regulation of protein kinase activity GO Biological Processes -34.3615088 109 More
GO:0048018 receptor ligand activity GO Molecular Functions -91.0736151 101 More
GO:0050730 regulation of peptidyl-tyrosine phosphorylation GO Biological Processes -27.1120967 60 More
GO:0050767 regulation of neurogenesis GO Biological Processes -15.7439029 55 More
GO:0050769 positive regulation of neurogenesis GO Biological Processes -12.1167088 37 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0051347 positive regulation of transferase activity GO Biological Processes -26.6059528 90 More
GO:0051960 regulation of nervous system development GO Biological Processes -17.2202851 64 More
GO:0051962 positive regulation of nervous system development GO Biological Processes -13.2580156 43 More
GO:0060284 regulation of cell development GO Biological Processes -22.9455891 78 More
GO:0061097 regulation of protein tyrosine kinase activity GO Biological Processes -4.69934335 14 More
GO:0061098 positive regulation of protein tyrosine kinase activity GO Biological Processes -4.90193440 11 More
GO:0070663 regulation of leukocyte proliferation GO Biological Processes -26.8242532 37 More
GO:0071900 regulation of protein serine/threonine kinase activity GO Biological Processes -19.5794055 63 More
GO:1902105 regulation of leukocyte differentiation GO Biological Processes -18.8286876 32 More
GO:1903706 regulation of hemopoiesis GO Biological Processes -16.2759166 33 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa04060 Cytokine-cytokine receptor interaction KEGG Pathway -61.0014447 66 More
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
interleukin-34 proteomics major adverse cardiovascular events[prognosis (bad)] acute ST elevation myocardial infarction Fan Q et al. Int Heart J. 2019
interleukin-34 proteomics cardiovascular death[prognosis (bad)] acute ST elevation myocardial infarction Fan Q et al. Int Heart J. 2019
All rights reserved: Soochow University Center for Systems Biology